The effect of nano-TiO2 on the bioavailability of large-scale antimony arsenic in urban environments

Advances in research on the effect of nano-titanium dioxide on the bioavailability of large arsenic species in urban environments

Due to its high specific surface area, stability, corrosion resistance, and photocatalytic properties, nano titanium dioxide (nTiO2) is mass produced and widely used. (The widespread use of nTiO2 inevitably leads to human exposure and environmental leakage, which in turn poses a threat to human health, animals, and the entire ecosystem. In recent years, articles published in the relevant fields of nTiO2 have grown rapidly, which also indicates that the safety of nTiO2 is being compromised. More and more attention has been paid, although existing studies have shown that (nTiO2 can absorb metals and organic pollutants through chemical binding such as electrostatic forces and chemical bonds, thereby increasing its bioavailability. However, nTiO2 is used as a carrier to promote There is a lack of systematic research on how pollutants are distributed and how they are potentially toxic after they enter the organism.

The Urban Water Environment and Water Ecology Research Group (Yan Changzhou team) of the Institute of Urban Environment, Chinese Academy of Sciences has applied nTiO2 as a research object since 2013 to systematically study its accumulation and distribution of pentavalent arsenic (As(V)) in large earthworms. The effects of toxic effects showed that (nTiO2 as an effective carrier significantly increased the accumulation of As(V) in large carcasses.(With increasing nTiO2 concentration from 2 mg-Ti/L to 20 mg-Ti/L. The cumulative amount of As(V) is 2.3 and 9.8 times the arsenic accumulation in the free state, respectively.The researchers found that the distribution of nTiO2 and As(V) in the large-scale larvae was significant by combining laser ablation with plasma mass spectrometry. Correlation (2.0 mg-Ti/L (nTiO2, R=0.676, P<0.01; 20.0 mg-Ti/L nano-TiO2, R=0.776, P<0.01). This also confirms the (nTiO2 carrier effect) In addition, the study found a very interesting phenomenon that the toxic effect of As (V) on large cockroaches was not consistent with its accumulation in large cockroaches. This study attempted to explain it from the perspective of subcellular distribution. Compared with the group, (As the concentration of nTiO2 increases, the increased As(V) is mainly distributed in gold. In the detoxification phase, while increasing (nTiO2 is mainly distributed in the metal-sensitive phase. As(V) and (The difference in the subcellular distribution of nTiO2 in large larvae indicates that the partial adsorption on As(V) on nTiO2 may be in large scales. In vivo (dissociated from nTiO2. Therefore, higher concentrations of (nTiO2 (20.0 mg-Ti/L) increased As(V) toxicity, while lower concentrations (nTiO2 (2.0 mg-Ti/L) decreased. The As(V) toxicity was due to the fact that the As(V) content in the metal sensitive phase remained essentially unchanged compared to the control; on the other hand, part of the As(V) was still adsorbed on the nTiO2.

The research results were published in the international journal Environmental Science and Technology (Environmental Science & Technology, 2016, DOI: 10.1021/acs.est.6b01215). The study was funded by the National Natural Science Foundation of China (41271484, 41401552, 41301346).

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