Beijing Precision Electromechanical Co., Ltd. introduces high precision OPC drum based CNC lathe

The high-precision OPC drum-based CNC lathes produced by Beijing Machine Tool Precision Electromechanical Co., Ltd. have been exhibited in Beijing recently and have attracted the attention of the industry. This GCK-1502 high-precision OPC drum base lathe is specially designed for high-precision machining of various toner cartridges and OPC drums. It has the characteristics of high processing precision, high processing efficiency, simple and convenient operation, and high reliability.

Obeticholic Acid (abbreviated to OCA, trade name Ocaliva,6-ECDCA)

Obeticholic acid increases the expression of FXR-regulated genes in rat hepatocytes  Obeticholic acidreduces expression of liver JNK-1 and JNK-2 . Obeticholic acid (256 μg/mL) shows complete inhibition of bacterial growth in all strains tested. Intestinal permeability remains unaffected after Obeticholic acid-addition to an IFN-γ-exposed intestinal epithelium of Caco-2 cells

In Vivo Obeticholic acid (10 mg/kg/day) completely reverted cholestasis induced by E217α. Administration of 6-ECDCA partially prevents the impairment in total bile acid output caused by E217α by increasing the relative abundance of β-MCA and TCDCA and TDCA[1]. INT-747 (10 mg/kg) and HS increases the pulmonary congestion in the animals.INT-747 does not improve renal pathology in the HS-fed animals[2]. INT-747 (5 mg/kg) significantly increases survival in BDL rats. INT-747-treated BDL rats exhibits a significant selective ileal increase in expression of pore-closing claudin-1. Ileal expression of ZO-1 is significantly up-regulated in INT-747-treated BDL rats[3].



Obeticholic Acid

OCA,Obeticholic Acid In Stock,Obeticholic Acid Cas 459789-99-2 In Stock,Cas 459789-99-2 Obeticholic Acid

Jinan Meigao Biopharmaceutical Technology Co., Ltd. , http://www.meigaobiopharma.com